OBJECTIVES: To gain insights into health technology assessments (HTA) landscape in Asia and to better understand international influence dynamics across interconnected HTA universe.  METHODS: Information on major Asian HTA agencies (NECA, HITAP, CDE, etc) was collected and analysed at the level of four data categories: agencies, institutions, people (members) and assessments. For each category a number of attributes were included (such as location, affiliations, memberships, type of technology, decision on technology). The Ni3 software was applied to add multiple types of connections between the datasets to conduct the analysis and visualize HTA networks. The tool enabled mapping of relationship links that represent direction and weight of influence, overlaying displayed stakeholders with visual charts summarizing sets of quantitative values (such as number of employees or budget) for visual pattern matching and comparison, and geographic analysis. RESULTS: The analysis revealed the initiated collaboration between HTA stakeholders in the Asia region.  In the centre of the Asian HTA ecosystem are located the most established agencies in Korea, Taiwan and Thailand where HTA already yields important evidence to inform policy and practice. The visual analysis revealed patterns of collaboration where agencies were 1) referring to each other; 2) referring to the same sources and academic institutions, and 3) absorbing the experience from well-established European HTA agencies such as NICE or IQWIG.   CONCLUSIONS: HTA has expanded globally and can be characterised by common patterns in interactions when looking at and refining the evidence required for the reimbursment. Rapidly growing in number and in influence HTA organizations in Asia are strengthening their abilities through collaboration with each other, by involving independent research institutions into the HTA process and by building upon European HTA experience.