THE PREVALENCE AND TYPE OF POTENTIALLY INAPPROPRIATE PRESCRIBING AMONG HOSPITALIZED GERIATRICS IN MALAYSIA
Author(s)
Akkawi ME, Nik Mohamed MH
International Islamic University Malaysia, Kuantan, Malaysia
OBJECTIVES: To identify the prevalence and types of potentially inappropriate medications (PIMs) and potentially prescribing omissions (PPOs) among community-dwelling geriatrics pre- and post-hospitalization. METHODS: A prospective cohort study involving patients ≥ 65 years old, on at least one medication for a minimum of 3 months prior to hospitalization, in a tertiary hospital in Malaysia. Data was collected from patients and their records after a signed consent form has been obtained. Patients were followed up until discharge. Medications at admission and discharge were reviewed to identify PIMs/PPOs using STOPP/START criteria Version 2. RESULTS: Of 300 patients, 44.3% (n=133) were females, with a mean age of 72 ± 6 years, length of hospital stay was 5.4 ± 3.7 days with a cumulative number of comorbidities upon admission of 3 ± 1.25 diseases. The prevalence of PIMs at admission was , which reduced at discharge to (p=0.014). The three most common PIMs on admission and discharge were vasodilators, that increase the risk of falls, and that were used on patients with persistent postural hypotension; metformin, that was used on patients with ClCr < 30 mL/min; and β-blockers, that were used on patients with frequent hypoglycaemic episodes. The prevalence of PPOs at admission was 47.6 % (143 patients, 207 PPOs), which increased at discharge to 48% (144 patients, 201 PPOs) (p=0.99). The three most common PPOs at admission and discharge were the omission of vitamin D supplement in patients with a history of falls, and the omission of angiotensin converting enzyme (ACE) inhibitor and ß-blocker in patients with documented coronary artery diseases. CONCLUSIONS: PIMs and PPOs are prevalent among community-dwelling geriatrics and hospitalization did not change their prevalence or type significantly.
Conference/Value in Health Info
2017-05, ISPOR 2017, Boston, MA, USA
Value in Health, Vol. 20, No. 5 (May 2017)
Code
PHP120
Topic
Epidemiology & Public Health
Topic Subcategory
Safety & Pharmacoepidemiology
Disease
Multiple Diseases