OBJECTIVES:  To explore pharmacy management and resources at Ministry of Health (MOH) hospitals in Saudi Arabia METHODS:  It is a 4-months cross-sectional national survey of pharmacy management and resources at MOH hospitals in Saudi Arabia. The study consisted of two-part demographic information, and the second part contained eighty-five questions divided into five domains drove from American Society of Health-System Pharmacists (ASHP) survey. The parts were pharmacy management and resources, prescribing and medication control, preparation of medications and dispensing, technology and clinical pharmacy services, drug monitoring and patients education. The 5-points Likert response scale system closed and ended questions used. An electronic questionnaire distributed to the one hundred eighty-five directors of pharmacies at MOH hospitals, and it analyzed the pharmacy management and resources section through survey monkey system RESULTS: The total number of responders was sixty-five hospital pharmacies; the repose rate was (35.13%). The majority of pharmacy services consisted of outpatient pharmacy 55 (96.5%), pharmacy store 49 (81.67%), inpatient pharmacy 48 (80%) and emergency pharmacy 40 (70.18%). The seldom finding of pharmacy services were satellite pharmacy 4 (8.16%), and clinical pharmacy 7 (13.73%). The total number prescriptions dispensed were (53,125) per day with an average (1,080,45) prescriptions per hospital. The total number of pharmacists were (618), and pharmacy technicians were (818) with a mean (11.14) pharmacists and (14.26) pharmacy technicians per hospital respectively. The majority of hospital pharmacies had job description 45 (73.77%), vision 44 (68.75%), and mission 42 (68.75%). While the tiny percentages found were pharmacy annual plan 23 (38.98%), and pharmacy strategic plan or competency of pharmacy staff 26 (43.33%). CONCLUSIONS: Most of the hospital pharmacies missed some an essential of pharmacy practice with emphasis on Human Resources and clinical pharmacy services. Implementing of the MOH pharmacy strategic plan with close monitoring is required for all hospitals in Saudi Arabia.