OBJECTIVES:  The purpose of this study was to test the effect of patient involvement levels, developed using different breast cancer risk scenarios on their intention to initiate breast cancer chemoprevention. METHODS:  In this experimental field study involvement was manipulated at 2 levels (high and low) and was developed using two scenarios. Breast cancer risk levels were considered using the Gail risk score. A breast cancer risk level of 16% with family history was used for low risk scenario and breast cancer risk level of 55% with family history and a breast biopsy was used for high risk scenario. Women across the Houston metropolitan area evaluated two chemoprevention drug decision aids after reading scenarios simulating high and low involvement. A pre-validated, self-administered survey instrument was used to measure their intention to start chemoprevention using a Likert scale ranging from 1 (strongly disagree) to 5 (strongly agree). ANCOVA and post-hoc analyses were done using SAS^®