OBJECTIVES: In a previous study, we had established a patient-reported syndrome scale: blood-stasis syndrome (PRS-BSS) which had satisfactory reliability and validity. This study aimed to assess the discriminant validity of the PRS-BSS for distinction in the two groups of patients and healthy people. METHODS: A sample of 50 cases of patients (age: 57±13years, 17 males) with blood stasis were enrolled. The patients mostly come from the department of cardiology, spleen and stomach, rheumatology. The patients completed the PRS-BSS and changhai pain feet pain score at the same time. 30 cases of healthy population(age: 53±11years, 11 males ) completed the PRS-BSS. The discriminant validity of the PRS-BSS were examined by using statistical methods such as correlation coefficient ,T test and analysis of variance. RESULTS: The scale was composed of 4 dimensions (activity, sleep, mood, and aggravation) and 10 items. The correlation coefficient of 4 dimensions and pain score were 0.703, 0.342, 0.461 and 0.495, respectively. The correlation coefficient of the PRS-BSS score and pain score was 0.741(P=0.000＜0.05). It was found that higher PRS-BSS scores were associated with the higher degree of pain. T test results showed that the scores of the patients with blood-stasis syndrome were obviously higher than those of healthy subjects (P＜0.001), which indicated the PRS-BSS could distinguish the known people. CONCLUSIONS: The discriminant validity was good. Two groups of the patients and healthy people can be distinguished clearly.The efficacy assessment of the PRS-BSS will be needed to evaluate in the futher research.