OBJECTIVES:  Perioperative blood loss and transfusion are important concerns in complex surgeries. Blood loss is associated with higher incidence of complications, transfusion rates, longer Length of Stay (LOS) and operating room time. The BS claims reduced intraoperative bleeding, lower transfusion rates and faster recovery times. This work estimates cost savings in spine fusion and hepatic surgeries using a low temperature RF Bipolar sealer versus standard monopolar electrosurgery (SME) from a Colombian provider perspective. METHODS:  An Excel cost-saving model was developed to assess the differential cost of using BS during spine fusion and hepatic surgeries, compared to SME. Variables included were transfusion rate, transfusion rate LOS, comparators related LOS, operating room time, direct costs of technologies, opportunity costs for operating room, hospital bed, and blood units. Clinical inputs were populated via a systematic literature search. Opportunity costs were estimated with hospital administrator, KOL input and the official Colombian tariff manual. RESULTS:  One partial hepatectomy and four spine surgery reference clinical publications were reviewed for this analysis. Spine procedures included Lumbar posterolateral, posterior spinal-fusion for degenerative lumbar scoliosis, posterior spinal-fusion for adolescent idiopathic scoliosis, and multilevel spinal-fusion surgery. For hepatectomy cases, there were cost savings in all cost categories, cost technology difference, blood bank, operating room and LOS, with USD$ 2.138 total saving per procedure. For spine-fusion surgeries, costs were higher (USD$ 255,2) for BS in cost technology difference, however they were offset by the lower costs in the blood bank, operating room and LOS. Dependent upon the type of spine surgery, total savings ranged from USD$ 78 to USD$ 2.327 per procedure. In all reviewed clinical works, lower blood loss was reported (-19% to -55%), compared to SME. CONCLUSIONS:  The use of BS during Hepatectomy and fusion-spine surgeries could represent important savings from the Hospital perspective compared to SME.