USE OF REAL-WORLD DATA TO ESTIMATE CARDIOVASCULAR EVENT RATES AMONG ELDERLY HIGH CARDIOVASCULAR RISK PATIENTS WITH MEDICARE SUPPLEMENTAL INSURANCE IN THE UNITED STATES

Author(s)

Quek RG1, Hardin J1, Bonafede MM2, Johnson BH2, Gandra SR3
1Amgen, Inc., Thousand Oaks, CA, USA, 2Truven Health Analytics, Cambridge, MA, USA, 3Amgen Inc., Thousand Oaks, CA, USA

OBJECTIVES: To estimate the rates of cardiovascular events (CVE) among elderly high cardiovascular risk patients METHODS: The Truven Health MarketScan Medicare Supplemental Database was used to hierarchically identify cohorts of elderly adults (age 65-75) with familial hypercholesteremia (FH), atherosclerotic cardiovascular disease (ASCVD) [myocardial infarction; unstable angina; ischemic stroke; stable angina; coronary revascularization; carotid stenosis; peripheral vascular disease; abdominal aortic aneurysm] or type 2 diabetes mellitus (T2DM) in 2006-2007; a variable-length follow-up was used to describe lipid-lowering therapy (LLT) and  rates of new CVE from 2008-2013.  The ASCVD and T2DM cohorts included patients prescribed statin at and ≤12 months post diagnosis; FH cohort included patients prescribed high intensity statin and ezetimibe concurrently for ≥30 days at and <12 month post diagnosis. The primary outcome was the presence of new CVEs, defined as an inpatient stay with a primary diagnosis of acute coronary syndrome ([ACS] includes myocardial infarction and unstable angina), ischemic stroke, heart failure, revascularization or cardiovascular-related death. RESULTS:

Conference/Value in Health Info

2016-05, ISPOR 2016, Washington DC, USA

Value in Health, Vol. 19, No. 3 (May 2016)

Code

PHS7

Topic

Epidemiology & Public Health

Disease

Cardiovascular Disorders

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