Reducing maternal mortality and perinatal mortality is part of the development objectives of a country. The indicator of potential productive years of life lost (PPYLL), is an impact measure that represents the lost that a society suffers as a result of premature deaths. OBJECTIVES: To estimate the PPYLL avoided by a prenatal healthcare program in a cohort of pregnant women insured by comparing the results with global indicators for the country. METHODS: The study was conducted in a cohort of 87,000 pregnant women who were under the prenatal healthcare program in the period from 2011 to 2013 in 16 cities of Colombia. The measuring outcome corresponded to maternal deaths and perinatal deaths. The indicators maternal mortality ratio and perinatal mortality rate were compared between the insurer and the country. The denominators of the insurer company were used to calculate the frequency of the event. The social impact was calculated by the PPYLL-ipc model in which deaths were weighted according to a balance between investment, production and consumption potential of each individual, according to the stage of productivity in which the deaths occurred. PPYLL were multiplied by the per capita GDP of Colombia in 2013 to estimate the average income that gained society by averted maternal and perinatal deaths. RESULTS:  the prenatal healthcare program in pregnant women avoids 43 perinatal deaths and 24 maternal deaths, equivalent to 1,417 PPYLL and $ 11'376.075 USD in productivity. CONCLUSIONS: prenatal healthcare program of the insurer compared with the results of the country showed a decline in maternal and perinatal deaths with consequent productivity gains to society.