OBJECTIVES: To evaluate the relationship between physician-assessment (per clinical judgment) and objective measures for disease severity assessments among RA patients in the EU and US. METHODS:  A multi-country multi-center medical chart-review study of RA patients was conducted in 4Q2011 among physicians (majority: rheumatologists) in hospitals/private practices to collect de-identified data on patients who were recently treated with a biologic as part of usual care. Physicians were screened for practice-duration and patient-volume and recruited from a large panel to be geographically representative in the EU (UK/Germany/France/Italy/Spain) and US. For successive patients visiting each center/practice during study period, physicians abstracted patient diagnosis, treatment patterns/dynamics and patient symptomatology/disease status incl. physician-assessment of disease severity (rated as mild/moderate/severe, per clinical judgment). RESULTS: In EU and US, 2208 and 851 patient charts were abstracted respectively; majority of the patients were on the 1st-line biologic (EU:74%; US:70%) while 20% and 23% respectively in EU and US were on 2nd-line biologic. Per physician-assessment, 49%/41%/9% were mild/moderate/severe in EU and 59%/35%/6% were mild/moderate/severe in US. Among those with available data, recent disease severity scores increased with increasing Physician-assessment-based severity level in both EU and US (mean values for mild/moderate/severe): Tender Joint Count - EU:2.5/5.3/7.4 vs. US:2.3/6.6/8.9; Swollen Joint Count - EU:1.3/3.6/5.3 vs. US: 1.5/5.0/6.7; 100mm VAS Score - EU:19.8/38.9/51.4 vs. US:17.2/47.0/48.6; HAQ Score - EU:0.8/1.4/1.5 vs. US:0.7/1.4/1.9; DAS28 score - EU:2.6/4.1/5.1 vs. US:2.5/4.0/5.3; Total Sharp Score - EU: 2.4/2.1/4.0 vs. US:3.1/2.3/7.0. Person correlation coefficient (r) comparing PGA (mild:1, modearate:2, severe:3) to individual objective disease severity measures were in the range of 0.79-1.00 in EU and 0.77-1.00 in US. CONCLUSIONS: Across the geographies, physician-assessment (per clinical judgment) strongly correlated with the objective measures of disease severity among RA patients, further strengthening the argument towards continued inclusion/use of simple physician-assessment scales in usual care practices around the world.