OBJECTIVES: Eating disorders are psychological conditions characterized by disturbed eating habits affecting approximately 30% of teen girls with significant effects on their health related quality of life (HRQL). The objective of this study was to compare and contrast psychometric properties of eating disorder specific HRQL instruments. METHODS: HRQL instruments were included in this review if they were available in English, and there was at least one publication citing psychometric properties. Study instruments were evaluated based on: conceptual model, versatility (type of disorder), practicality, depth (<15%), reliability (internal consistency and test-retest), construct validity (convergent and divergent or confirmatory factor analysis), and responsiveness. RESULTS: Six instruments were identified: Eating disorder quality of life (EDQOL), eating disorder quality of life scale (EDQLS), health related quality of life in eating disorder and its abbreviated version (HeRQoLED v2), Quality of life for eating disorders (QOL ED), and eating disorder well-being scale (EDwell). All instruments were developed for self-administration, taking 5-15minutes to complete, designed for use in female teens/adults supported by construct validity data, with most scales supporting group- as opposed to individual- level decision making. Only HeRQoLEDv2 was developed for use in both genders.  Lack of meeting study criteria may be attributed to missing data, e.g., test-retest reliability. None of the six instruments met all study criteria; however, EDQLS and HeRQoLEDv2 met almost all study criteria.  CONCLUSIONS: All eating disorder instruments reviewed were developed within the last 10 years with available data being inadequate to assess all scales.  Similar to Tirico et al. (2000), in the present study EDQLS and HeRQoLEDv2 met most of the study criteria, in contrast,  EDQOL was excluded from this list due to missing data, Study data supported individual level decision making only for the HeRQoLEDv2.