OBJECTIVES: To estimate prevalence of Adult ADHD (AADHD) symptoms among university-based students across multiple academic disciplines.  METHODS: A cross-sectional research design, utilizing convenience sampling and self-administered paper and pencil questionnaire technique, was adopted. Adult students (>18 years) were recruited from a university campus in New York City area. AADHD Self-Report Scale- v1.1 (ASRS v1.1), a pre-validated screening instrument, was used to assess performance along inattention, hyperactivity/impulsivity and combined symptom sets of adult ADHD. A score of 17 or more on an ASRS v1.1 scale between 0 and 72 indicates the likelihood of ADHD, whereas a score of 24 or more indicates immense likelihood of ADHD. Individual component scores of ASRS were compared for students from six different schools and programs within the university.  RESULTS: The final sample consisted of 638 students from six different schools representing multiple academic programs. Using ASRS-v1.1 symptom cut-off threshold, a prevalence rate of ADHD symptoms ranging from 21.2% to 66.2% (indicating likelihood and immense likelihood of ADHD respectively) was observed for the general student sample. Only 3.4% of the participants had been previously diagnosed with ADHD. The prevalence of self-reported ADHD symptoms was higher in the age group of 18-23 years (81.3%) and was greater in females (53.1%). A majority of students had the inattentive type of symptomatology (72.72%). With regard to different disciplines, prevalence rates ranged from 49% (pharmacy school) to 5.9% (school of education). More undergraduate students reported AADHD symptoms (70.9%) compared to graduate students (28.4%). Students in healthcare discipline reported greater ADHD symptomatology (54.6%) compared to students in non-healthcare fields.  CONCLUSIONS: Symptoms of AADHD appear to be more prevalent in student populations than documented evidence would suggest. Among many that are affected, most are either unaware of the condition or undiagnosed. These findings have implications for students’ overall health and academic performance.