OBJECTIVES: The aim of this research is to examine the factors which determine the vaccination in relation to the standpoint of the parents. METHODS: A descriptive, cross-sectional, prospective and quantitative study made in and around Pápa, Hungary. The research was carried out between 15 January, 2014 and 31 May, 2014. We evaluated 95 appraisable questionnaires that were completed by parents raising children between the age of 0-18.  Descriptive statistics with frequency range, Chi2-test was performed with Microsoft Excel 2010. RESULTS: The information possessed by parents significantly shape their opinion on vaccination (p<0,001) while vaccination is 97.5%. Parents with young age (between 18-30) possess less information regarding vaccination than parents over 40 (p<0.05). 12.6% of the parents are not able to name the diseases which their children are being vaccinated; 27.3% of the questioned do not know the reactions and possible side effects to the vaccination which shows relation to the age (p<0,001). It is determinant for parents that in what degree the vaccinated disease exists and known at present (p<0.00). More than half of the questioned parents think that the knowledge they possess is not enough regarding the vaccines, while almost 100% would take part in an orientation. Parents attach importance to the advice of the GP and the health visitor. However, 50% of them seek answers to their question through the media. CONCLUSIONS: The information possessed by parents significantly shapes their opinion on vaccination but not the vaccination itself. Many of them do not know the disease specific effectiveness of the applied vaccination, possible side effects, and they do not apply the vaccination consciously.  It is necessary to organize further comprehensive information sharing for the parents during an orientation, which is supported by the results of our research.