OBJECTIVES: Real World Evidence (RWE) is likely to become increasingly important in decisions that affect patient’s access to medicines worldwideHowever, absence of long-term patient registries and electronic documentation constitute the greatest barriers for generating RWE studies in Poland. Therefore, an exploratory survey was undertaken to map current awareness and expectations of physicians related to practical outcomes data and to identify pharmaceutical industry’s role in RWE generation. METHODS: The study was conducted across 6 doctors’ specialties: diabetology(n=30), virology(n=42), oncology(n=28), hematology(n=62), dermatology(n=14) and psychiatry(n=72), others(n=3) from outpatient and inpatient care. The survey consisted of qualitative and quantitative questions covering areas such as the most trusted sources of RWE in Poland, pharma role in RWE generation vs. government’s contribution, most desired type of RWE. The questionnaires were collected Sept-Nov 2014 (the total number of responses received n=251). Data were analysed using simple descriptive statistics. RESULTS: Physicians demonstrated high degree of interest in evidence on practical outcomes, particularly in data on safety and effectiveness of treatment (over 90% of responders); at the same time 1 out of 5 doctors claimed that data on effectiveness are hardly accessible in Poland. Interesting differences regarding desired real life data were observed across specialties: i.e. treatment pathways and prescribing patterns were frequently valued by diabetologists (87%), while quality of life was often quoted by hematologists (87%). For psychiatrists (69%) data on direct treatment costs are highly important whereas data on patient compliance was most often mentioned by oncologists (79%). CONCLUSIONS: The research showed high physicians’ interest in practical evidence and the variety of RWE perception. The differences in priorities between specializations indicate unmet needs in therapeutic areas. Broadening doctor’s and other stakeholders knowledge in RWE data significance and improving its accessibility could be crucial for gaining doctor’s advocacy for shaping RWE landscape in Poland and, consequently, for improving patient’s treatment results.