OBJECTIVES: Patient-reported outcomes (PROs) are critical to advancing patient centered care. Recording PROs in real-time concurrent with clinician-reported outcomes represents the most direct and accurate comparative assessments of disease and treatment impact. This study sought to compare patient-generated global assessment (PGA) and physician global assessment (PhGA) rheumatoid arthritis (RA) scores to determine patient-physician discordance for rates of disease and treatment impact on perceived well-being. METHODS: From 1/1/2012 to 12/31/2013, 79 rheumatologists in 35 practices participating in a payer-sponsored rheumatologist-developed RA pathway program incorporated use of a point-of-care DST, which required a clinical disease activity index (CDAI) assessment at each physician visit. Components of the CDAI included PhGA and PGA scores, which were captured over the study period; lower scores are associated with better patient status. Paired t-tests and linear regression were used to analyze and compare scores for discordance. RESULTS: