OBJECTIVES:   To describe and evaluate health resource use (HRU) of schizophrenia patients enrolled to JANSSEN CONNECT® (JC). METHODS: This is a multi-center, retrospective medical chart review of patients enrolled in JC, a comprehensive information and assistance program that supports patients after a healthcare professional has determined a Janssen long-acting injectable atypical antipsychotic to be the most clinically appropriate treatment option.  Data collected included demographic and clinical characteristics, HRU, outpatient and injection appointments (missed and completed) and medication usage. The index date was defined as LAI initiation date where new users initiated LAI on/after JC enrollment while continuous users initiated LAI prior to enrollment.  Descriptive analysis was conducted to evaluate the demographic, clinical characteristics and HRU of JC enrollees at 6-month pre- and post-index periods. Comparative analysis on matched JC and non-JC patients to evaluate effectiveness of the program is on-going. RESULTS: A total of 102 JC patients were included (15 continuous users and 87 new users). The mean age was 41 years (SD=13), 63% were males, 64% were covered by Medicaid, or Medicare, or dually covered, 63% lived with family/friends and 29%, 30% and 25% had comorbidity conditions of depression, anxiety and bipolar disorder, respectively.  In the pre-index period, 22% of JC patients had any use of inpatient hospitalization, emergency room (ER) or crisis stabilization unit (20%, 1% and 5%, respectively) and 77% had outpatient visits.  Pre-index oral atypical antipsychotics (73%) and antidepressants (59%) were commonly used.  In the post- index period, 18% of patients had any use of inpatient hospitalization, ER or crisis stabilization unit (15%, 2% and 3%, respectively) and 84% had outpatient visits. Post-index oral atypical antipsychotics and antidepressant use was 59% and 57%, respectively.   CONCLUSIONS: Preliminary evidence shows numerically lower inpatient, ER and crisis unit utilization from pre- to post-index period among schizophrenia JC enrollees.