COMPARISON OF THE IMPACT OF HUMAN VERSUS ANALOGUE INSULINS ON GLYCOSYLATED HEMOGLOBIN IN A POPULATION WITH DIABETES MELLITUS COLOMBIA
Author(s)
Machado J, Medina D
Universidad Tecnológica de Pereira, Pereira, Colombia
OBJECTIVES: To compare the effect on metabolic control between conventional and analogues insulins. METHODS: Retrospective cohort study in primary care centers in cities of Pereira and Manizales from Colombia. Monitoring period 18 months to patients diagnosed with diabetes mellitus type 1 and 2 selected by stratified random sampling, of pay regime members of the Health System of Colombia, treated with conventional and analogues insulins (glargine, glulisine, aspartate, detemir) for at least 6 months. Collecting data from the clinical records and analytical results for each patient. Comparison groups according to the type of insulin received were created (insulin glargine vs NPH; NPH / glargine vs regular / glulisine). Primary and secondary variables: initial HbA1c measurement and comparison at 6 months and 3 and 18 months respectively. RESULTS: CONCLUSIONS: We did not find that analogue insulins were superior to human in glycemic control effect and a high percentage of patients did not meet the recommended treatment, which requires implement measures to improve the monitoring and control of diabetes mellitus.
Conference/Value in Health Info
2015-05, ISPOR 2015, Philadelphia, PA, USA
Value in Health, Vol. 18, No. 3 (May 2015)
Code
PHS12
Topic
Clinical Outcomes, Epidemiology & Public Health
Topic Subcategory
Comparative Effectiveness or Efficacy, Safety & Pharmacoepidemiology
Disease
Diabetes/Endocrine/Metabolic Disorders