OBJECTIVES: The patient centered medical home (PCMH) is a model of delivering primary care with features such as comprehensive, coordinated, continuous and accessible care. The high cost and intensive long-term care requirements of cancer survivors makes this population a perfect candidate for the PCMH model of care. The objective of this study is to determine if access to a PCMH is associated with lower healthcare costs and utilization among cancer surviviors. METHODS: The study population was drawn from the 2008-2012 data of the Medical Expenditure Panel Survey. The final sample included 7,081 adults with a history of at least one type of cancer diagnosis other than non-melanoma skin cancer (“cancer survivors”), who reported having a usual source of care (USOC), were eligible for the required supplemental questionnaire on access to care and were in-scope throughout the survey year. A subject’s USOC is defined as a PCMH based on the American Association of Pediatrics’ concept of a medical home and published literature. Healthcare utilization included the number of emergency department (ED) visits, hospital admissions, office-based visits and prescription medications, which were analyzed using negative binomial regression models. Medical expenditure was analyzed using generalized linear model with gamma distribution and log link function. RESULTS: Cancer survivors with a PCMH had a lower incidence of ER visits (Incidence Rate Ratio (IRR) =0.77, 95% CI: 0.66-0.90) and consumed fewer prescription medications (IRR=0.93, 95% CI: 0.88-0.99). There was no association between access to medical homes and outpatient (IRR=0.96, 95% CI: 0.90-1.03) or inpatient (IRR=1.06, 95% CI: 0.90-1.24) visits and total medical expenditure (β=-0.05, 95% CI: -0.17-0.07).  CONCLUSIONS: Access to a PCMH was associated with reduced ED visits and prescription drugs use among cancer survivors. However, no difference in inpatient or outpatient visits, or overall medical expenditures were found.