OBJECTIVES: Medication non-adherence causes hundreds of billions of dollars in avoidable costs. This study sought to survey the existing medication adherence programs of managed care organizations (MCOs). METHODS: Thirty MCOs were interviewed in Spring 2014 about their current and future medication adherence programs. 19 small (<200,000 members) and 11 large (≥200,000 members) filled out a 19-question (excluding 6 on program characteristics) survey covering the strategies and methods used to improve patient adherence. RESULTS: The MCOs dedicate the majority of adherence resources toward cardiovascular disease states but most are looking to expand to more disease states. Just two (7%) of the MCOs surveyed use predictive analytics to target patients for their intervention programs while 12 (40%) use retrospective adherence measures. 75% of MCOs are looking to expand their adherence programs while 60% specifically plan to use predictive analytics in the future. Only two (7%) only used outsourced interventions, 10 (33%) used in-house and 18 (60%) used some combination of the two. 20 (67%) MCOs used live call interventions and only 2 (7%) used text reminders. 14 small (74%) and 9 (82%) large MCOs used direct mail interventions. 20 (67%) of the MCOs rated their intervention programs to be “moderately effective.” CONCLUSIONS: Most MCOs prioritize adherence to cardiovascular disease medication but most are also interested in expanding their programs. Few MCOs use enhanced platforms to select patients for interventions but many plan on expanding their platforms. MCOs intervened to improve adherence largely through provider-centric channels and with a combination of in-house and outsourced methods. Many MCOs are interested in adopting a platform that identifies high-value interventions, like AllazoHealth, since current programs aren’t personalized and are perceived as ineffective.