THE ASSOCIATED FACTORS OF NEUROPATHIC PAIN AMONG CHRONIC LOW BACK PAIN PATIENTS IN SOUTH KOREA- FINDINGS FROM THE NLBP OR

Author(s)

Kim J¹, Hong JT², Lee C³, Kim K⁴, Suk K⁴, Kim J⁵, Park Y⁶, Chang B⁷, Jun DS⁸, Kim Y⁹, Lee J¹⁰, Min W¹¹, Lee J¹², Park S¹³, Oh I¹⁴, Hong J¹⁵, Shin H¹⁶, Kim W¹⁷, Kim J¹⁸, Lee J¹⁹, Kim I²⁰, Ha Y²¹, Im S²², Kim SW²³, Han I¹², Shin J⁵, Rim B²⁴, Seo B²⁵, Kim Y²⁵, Lee J²⁶
¹Inje University Ilsan Paik Hospital, Ilsan, Korea, Republic of (South), ²The catholic university of Korea, St. vincent’s hospital, Suwon, Korea, Republic of (South), ³Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of (South), ⁴Gangnam Severance Hospital, Yonsei University Health System, Seoul, Korea, Republic of (South), ⁵Inje University Sanggye Paik Hospital, Seoul, Korea, Republic of (South), ⁶Hanyang University Guri Hospital, Seoul, Korea, Republic of (South), ⁷Seoul National University Hospital, Seoul, Korea, Republic of (South), ⁸Gachon Universtiy Gil Medical Center, Incheon, Korea, Republic of (South), ⁹Seoul St. Mary’s Hospital of the Catholic University of Korea, Seoul, Korea, Republic of (South), ¹⁰Kyung Hee University Hospital, Seoul, Korea, Republic of (South), ¹¹Kyungpook National University Hospital, Kyungpook, Korea, Republic of (South), ¹²Pusan National University Hospital, Pusan, Korea, Republic of (South), ¹³Korea University Anam Hospital, Seoul, Korea, Republic of (South), ¹⁴Incheon St. Mary’s Hospital of the Catholic University of Korea, Incheon, Korea, Republic of (South), ¹⁵Korea University Ansan Hospital, Ansan, Korea, Republic of (South), ¹⁶Kangbuk Samsung Hospital, Seoul, Korea, Republic of (South), ¹⁷Gachon University Gil Medical Center, Incheon, Korea, Republic of (South), ¹⁸Korea University Guro Hospital, Seoul, Korea, Republic of (South), ¹⁹Chonnam National University Hospital, Chonnam, Korea, Republic of (South), ²⁰Keimyung University Dongsan Hospital, Deagu, Korea, Republic of (South), ²¹Severance Hospital, Yonsei University Health System, Seoul, Korea, Republic of (South), ²²Soonchunhyang University Hospital Bucheon, Bucheon, Korea, Republic of (South), ²³Yeungnam University Hospital, Yeungnam, Korea, Republic of (South), ²⁴Sun Medical Center, Deajeon, Korea, Republic of (South), ²⁵Pfizer Pharmaceuticals Korea Ltd., Seoul, Korea, Republic of (South), ²⁶Korea University College of Medicine, Seoul, Korea, Republic of (South)

OBJECTIVES: Low back pain (LBP) patients with neuropathic pain (NP) had substantially impaired quality of life. We investigated possible factors associated with NP in chronic LBP patients.

METHODS: Data were extracted from the NLBP OR [the NP in chronic LBP patients; Korean epidemiological study]. It was a multicenter and cross-sectional study where 1,200 patients older than 20 years of age with chronic LBP longer than 3 months, with a visual analog scale (VAS) pain score higher than 4, and with pain medication at least 4 weeks prior to enrollment were recruited at 27 general hospitals from December 2014 to May 2015. Potential factors related to NP were age, sex, LBP duration from diagnosis, Quebec Task Force Classification for Spinal Disorders (QTFC-SD), comorbidities, and pain VAS and were collected by medical chart review. Douleur Neuropathique 4 (DN4) was used for diagnosis of NP (DN4≥4).

RESULTS: Analysis was performed on 880 patients (mean age 64 years, male 34%) who had complete data of all measured variables. 362 (41%; mean age 63 years, male 40%) patients were classified as NP. In multiple logistic regression analysis, independently associated factors of NP prevalence were male (adjusted odds ratio, 1.7; 95% Confidence Interval, 1.2-2.3) and having pain of severe intensity compared to moderate pain (1.8; 1.4-2.4). In addition, compared to pain without radiation, pain with proximal extremity radiation (3.5; 1.8-6.8), pain with distal extremity radiation (7.4; 4.1-13.6), pain with radiation and neurologic finding (7.6; 3.6-16.3), spinal nerve root compression (5.9; 2.8-12.4), and spinal stenosis (4.6; 2.3-9.2) were respectively associated with NP prevalence.

CONCLUSIONS: When physicians treat chronic LBP, more attention should be given to those patients with related factors of NP.

Conference/Value in Health Info

2017-11, ISPOR Europe 2017, Glasgow, Scotland

Value in Health, Vol. 20, No. 9 (October 2017)

Code

PSY20

Topic

Epidemiology & Public Health

Disease

Systemic Disorders/Conditions

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