ESTIMATE EUROPEAN CANDIDATES FOR BRONCHOSCOPIC LUNG VOLUME REDUCTION (BLVR) TECHNOLOGIES IN THE TREATMENT OF SEVERE EMPHYSEMA
Author(s)
Busca R1, Rott C2, Witt C3
1PneumRx Ltd, London, UK, 2PneumRx GmbH, Düsseldorf, Germany, 3Charité - Medical University, Berlin, Germany
OBJECTIVES: Since CE mark was granted to BLVR technologies valves and coils, respectively in 2003 and 2010, procedure volumes grew significantly in Germany which was among the first country to adopt these techniques. Objectives of this research are exploring trend of adoption and estimating the number of candidates for BLVR in 9 European countries. METHODS: we used data from the German Federal Statistics Office databases for the period 2010-2015. This is the only database available in Europe differentiating BLVR procedures to retrospectively draw therapy uptake. Having valves two different indications, we excluded codes associated to the implant of 1-2 valves being mainly used to treat air leak. For coils we computed code-specific volume and we approximated the number of patients treated per year using average number of units per procedure from literature. RESULTS: Our analysis suggests a pronounced growth in BLVR treatments in the study period, reaching an adoption rate of 23 patients per million inhabitants in 2015 in Germany across 146 different clinics with 73 clinics performing less than 10 procedures; by excluding outliers clinics (<3 and >100 procedures) the average number of procedures per clinic per year is 17 . Under the indication of severe emphysema, nearly 10,000 patients per year can be considered for BLVR in the 9 selected European countries by applying a scenario similar to the German one. CONCLUSIONS: Since CE mark several new trials and Health Technology Assessments were published helping physicians optimise patient selection and driving the inclusion of BLVR technologies in the clinical guidelines. The reality is that with few exceptions the adoption of BLVR techniques outside Germany is still on its infancy. Many factors can influence diffusion: guideline adoption, physicians’ awareness, capacity, organisational factors, referral pathways, socio-economic indicators and coverage recommendations.
Conference/Value in Health Info
2017-11, ISPOR Europe 2017, Glasgow, Scotland
Value in Health, Vol. 20, No. 9 (October 2017)
Code
PMD143
Topic
Real World Data & Information Systems
Topic Subcategory
Health & Insurance Records Systems
Disease
Respiratory-Related Disorders