OBJECTIVES:

Antibiotics, miracle drug, are efficient in treating various bacterial illnesses. Excessive or irrationals use of antibiotics are major global public health challenge leading to antibiotic resistance. In Nepal bacterial infections (lower respiratory infections, diarrheal diseases and tuberculosis, urinary tract infections and sexually transmitted infections) diseases are significant public health burden. Commonly used antibiotics are found to be resistance to the local isolates of these diseases. This research aims to the measurement of antibiotics utilization in terms of defined daily dose(DDD)/100 bed-days in MICU in the CMCTH, Nepal according to ATC (anatomic-therapeutic-chemical) classification system.

METHODS:

A prospective observational study was conducted on 157 patients MICU of the CMCTH from 17 July to 18 September 2016. The demographic data, disease state, clinical history and investigation, prescription of antibiotics and their cost were recorded.

RESULTS: ICU mortality rate was