BURDEN OF DISEASE ON CHRONIC HEART FAILURE PATIENTS- A MULTINATIONAL CROSS-SECTIONAL SURVEY IN REAL WORLD SETTING
Author(s)
Viriato D1, Proenca CC2, Lahoz R3, Agrawal R4, Cotton S5, Jackson J5, Calado F3
1Novartis Farma – Produtos Farmacêuticos S.A., Porto Salvo, Portugal, 2Wellmera AG, Basel, Switzerland, 3Novartis Pharma AG, Basel, Switzerland, 4Novartis Healthcare Pvt. Ltd., Hyderabad, India, 5Adelphi Real World, Bollington, Macclesfield, UK
OBJECTIVES: To understand the burden of CHF on patients. METHODS: A cross-sectional survey was conducted and patient record forms (PRF) were completed by 563 cardiologists for 4903 CHF patients. The same patients were invited to complete a patient self-completion questionnaire (n=2460). Pooled data for 10 countries (Argentina, Brazil, China, Colombia, France, Japan, Mexico, Russia, Saudi Arabia and Turkey) is presented. RESULTS: The mean (SD) patient age was 66.7 (11.9) years; 58% patients were male and mean BMI was 25.9 (4.6) kg/mThe most common symptoms were dyspnoea when active (67%) and fatigue (58%). Considerable disruption in everyday life (score of ≥5 on a 1-no disruption to 10-severe disruption scale) was reported by 56% patients with a mean score of 4.9 (2.4). Of the 2452 patients, 17% were employed; and of the 85 unemployed patients responding, 44% reported CHF as the reason for their unemployment. Mean EQ-5D score (n=2398) was 0.71 (0.29); the most affected domain (moderate to severe) was pain/discomfort (55%) followed by problems in performing routine activities (46%), anxiety/depression (43%) and difficulty in walking about (43%). On average, patients spent 64.9 (148.8) minutes/visit travelling to and from the hospital. Assistance from a professional caregiver (n=2417) was reported by 9% of patients with a mean of 24.1 (28.9) hours/week of required assistance (n=200). PRF data showed that 41% of patients were hospitalised at least once for CHF in the year prior to the consultation, and of those hospitalised, 24% were readmitted within the same year CONCLUSIONS: CHF adversely affects patients’ quality of life and introduces considerable disruption due to (repeated) hospitalisations.
Conference/Value in Health Info
2017-11, ISPOR Europe 2017, Glasgow, Scotland
Value in Health, Vol. 20, No. 9 (October 2017)
Code
PCV127
Topic
Patient-Centered Research
Topic Subcategory
Patient-reported Outcomes & Quality of Life Outcomes
Disease
Cardiovascular Disorders