OBJECTIVES: To evaluate the health related quality of life (HRQoL) and costs of treating CML in a hospital setting in Bulgaria.

METHODS: Prospective, observational, 1 year lasting study of real life therapy of 42 hospitalized patients in Alexandrovska university hospital in Sofia. HRQoL was evaluated with SF-36 questionnaire. Costs data were collected from clinic and hospital pharmacy`s electronic program. Descriptive statistic and t-test analysis was also performed. The point of view is that o the hospital and patients for 1 year time.

RESULTS: CONCLUSIONS: Although the therapy is very expensive it provides suggests good control of this considered as a malignant disease and relatively high quality of life of CML patient population.