Today, depression is considered as one of the most common diseases. According to WHO, the beginning of the XXI century depressive disorders accounted about 40% in total mental pathology. Annually in the world about 200 million people suffer from depression, and this figure is actively growing. In this regard, the priority of health systems is an effective work aimed at the prevention and treatment of this disease. The aim of our study was to analyze the epidemiological data on the burden disease, depressive disorders caused by the results of the analytical data on network internet survey. As a result of the search, it is revealed that over the past few decades, the problem of depressive disorders is of particular relevance for the system of medical care. In the process of the project’s realization of «European research epidemiology of mental disorders» almost 13% respondents showed the signs of psychotic depression at definite time in their lives and 4% – in the last 12 months. The total number of people with psychotic depression has reached over 21 million in Europe. According to WHO «epidemic threshold» of suicides – 9 people per 100,000 population, but in our country, this figure ranges 40. All this leads to major economic losses to society and negative socio-economic effects that create the «burden of disease». Thus, the above data indicate that in terms of the economic burden of depression’s prevalence in our country has negative consequences on the necessity of the introduction of effective medical technologies for prevention and treatment of diseases. urden of depression’s prevalence in our country has negative consequences on the necessity of the introduction of effective medical technologies for prevention and treatment of diseases.