OBJECTIVES : Genomic testing is increasingly becoming popular in many disease areas to help guide treatment decisions. However, treatment changes and trends as a result of genetic testing in mental health disorders is unknown. We used RealHealthData, a US nationwide transcription database to assess trends in genomic testing from 2008 to 2017 and understand treatment changes among patients due to testing.

METHODS : RealHealthData works with medical transcription companies across US to build a database of detailed narrative medical records, providing a unique perspective on patient conditions and physician interaction. Using natural language processing, database was searched for mentions of genetic testing and depression, schizophrenia, anxiety and ADHD. Individual patient chart data was abstracted for diagnosis, demographics, testing date and treatment change as a result of genetic testing.

RESULTS : Of the 724,213 depression patients, 2359 underwent genetic testing such as GENECEPT^® and GENESIGHT^{® CONCLUSIONS : The slow but increasing trends in genetic testing among patients and treatment changes suggest the growing importance of personalized medicine in mental health. Medical transcription data can provide early insights into clinicogenomic evidence in patients with psychiatric disorders. This data alongside claims, EMR and genomic data can provide valuable insights into the precision HEOR field, guide treatment decisions in psychiatric disorders and help change the paradigm from treating the illness to treating the individual.}