GLOBAL PNEUMOCOCCAL VACCINATION IN ELDERLY- A SYSTEMATIC LITERATURE REVIEW

Author(s)

Huang M, Yang HK
Merck & Co., Inc, West Point, PA, USA

OBJECTIVES: Elderly population has a higher chance of developing pneumococcal disease and is recommended to receive pneumococcal vaccination by government agencies around the world. In the U.S., CDC reports pneumococcal vaccination coverage in the elderly annually. However, the pneumococcal vaccination coverage in elderly outside of the U.S. is unclear. The objective of this study was to review published data on the current global pneumococcal vaccination.  METHODS: A systematic literature review was conducted in PubMed/MEDLINE to identify studies published between 2011-2013 that have assessed pneumococcal vaccination coverage in elderly population aged 65 years or older. RESULTS: Thirty-nine studies that assessed pneumococcal vaccination among elderly were identified, with 16 from North America (NA), 11 from Western Europe (WE), 7 from Asia Pacific (AP), 3 from Latin America (LA), and 2 from the Middle East (ME). No studies were found in Eastern Europe (EE) and Africa. Around 70% of identified studies were from NA and WE, where most governments have recommended pneumococcal vaccines for elderly. While many countries in AP, LA, and EE have similar recommendations, only a few countries have conducted studies to assess the vaccination coverage to explore the policy uptake. Limited countries in Africa and ME have national recommendations, which could be the reason why the related research has been scant. Overall, 15 studies explored pneumococcal vaccination for general older population, while the rest (n=24) assessed coverage for elderly with certain conditions or sociodemographic characteristics, or in specific settings. Population-based studies showed that the pneumococcal vaccination coverage in elderly ranged 49.8%-68.6% for NA (n=5),36.4%-50.9% for WE (n=2),18.4%-61.0% for AP (n=5),8.7%-44.3% for LA (n=2), and 72% for Israel (n=1). CONCLUSIONS: Limited data on pneumococcal vaccination in elderly were reported for countries in LA, AP, EE, ME, and Africa regions. Further studies that examine pneumococcal vaccination in these regions are needed to evaluate the implementation of related policy.

Conference/Value in Health Info

2014-05, ISPOR 2014, Palais des Congres de Montreal

Value in Health, Vol. 17, No. 3 (May 2014)

Code

PIN76

Topic

Patient-Centered Research

Topic Subcategory

Adherence, Persistence, & Compliance

Disease

Infectious Disease (non-vaccine)

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