OBJECTIVES:  The Cervantes short-form (Cervantes-SF) scale is a psychometrically valid tool assessing the impact of menopausal symptomatology on patient quality-of-life. The objective was testing the need for rescaling the overall score of the scale in subjects sexually inactive. METHODS:  This was a post-hoc analysis of a study carried-out to test the psychometric properties of the Cervantes-SF in menopausal women. For this analysis, we used the subsample of outpatients women 45-65 years with menstrual problems associated with the climacteric syndrome who informed to be sexually inactive. The Cervantes-SF scale was used. Overall score was calculated using the original correction instructions which calculates the overall score adding the four primary domains of the scale (menopause and health, psychological, couple relations and sexuality) and dividing by four, and alternative method excluding the sexuality domain in the total punctuation and dividing by three. Agreement was tested using the paired t-test and the intraclass correlation coefficient (ICC). RESULTS:  Sixty-four out of 317 women [58.5±4.2 years (mean ± standard deviation)] sexually inactive were included in the analysis: 90.6% were post- and 9.4% were peri-menopausal. Overall score with four domains was 39.4 (13.1) and 38.4 (13.0) excluding sexuality domain; difference; 1.0 (95% bootstrap confidence interval: -3.2; 1.2, p=0.376). ICC was 0.872 (0.789; 0.922, p<0.001) and Pearson correlation coefficient was 0.772 (0.691; 0.845, p<0.001). Excluding the sexuality domain only modified Cronbach’s alpha from 0.820 to 0.822. CONCLUSIONS: According with these findings, rescaling of the overall score of the Cervantes-SF scale in menopausal women sexually inactive does not require excluding the sexuality domain from the overall scale scoring, while allowing clinicians to explore this domain when pertinent.