OBJECTIVES: To translate and cross-culturally adapt the Prothesis Evaluation Questionnaire (PEQ) into Finnish then test its psychometric properties on adult lower-extremity prosthetic users. METHODS: The PEQ was adapted into Finnish adhering the ISPOR translation guidelines. Study participants completed the following: the Finnish PEQ, patient-reported overall pain and health using a visual-analogue scale, a physical activity questionnaire, and the 15D health-related quality of life (HRQoL) instrument. The study poulation comprised 130 adult patients (65% men) who had undergone major lower-extremity amputation for various reasons were rehabilitated to prosthesis use and had completed all questionnaires. Reliability testing included internal consistency, the floor-ceiling effect, and test-retest assessment for which participants completed the PEQ twice separated by a 2-week interval. Validity assessment included criterion validity testing and linear regression analyses in the predictors of the 15D age and gender standardized regression coefficients β. RESULTS:  Minor linguistic changes were made for Finnish cultural adaptation. The mean (SD) PEQ scale score was 65.1 (23.7). Cronbach’s alphas ranged from 0.67 to 0.96 for the scales. The total score showed no floor or ceiling values. Reproducibility of the 10 separate scales ranged from 0.78 to 0.87. Seven of the 10 scales had statistically significant correlations with general pain and six scales with general health. Linear regression analyses identified large relationships between the 15D and four of the PEQ scales: Ambulation, Social burden, Usefulness and Well-being. CONCLUSIONS:  The Finnish version of the PEQ was succesfully adapted for Finnish prosthetic users. Psychometric testing of the Finnish version of the PEQ showed good internal consistency and test-retest reliability. The PEQ is valid in assessing the HRQoL in Finnish adult major lower-extremity amputees who have rehabilitated to become lower-extremity prosthesis users.