DESCRIPTION: The explosion of big data, the rise of health IT, genomic information, and social media, as well as the increased focus on patient centricity, privacy issues, and reproducibility of research results, has rendered the current ISPOR Code of Ethics outdated. In addition to the changes in the market, ISPOR has grown tremendously in membership and geographic reach since its 2008 publication. ISPOR’s influence on global health policy is likely to increase in the coming years. This potential could be undermined by perceptions of bias or other ethical issues surrounding the conduct of HEOR. Speakers will discuss the additions to the Code, the publications section, and the increased role of patients and other stakeholders on ISPOR’s Code of Ethics. Comments and feedback from the audience are appreciated!