OBJECTIVES:  The objective of the study is to evaluate the knowledge, attitude and perception of medical, dental and pharmacy students in AIMST University on the progress of Zika Virus. METHODS:  A cross-sectional observational study on a convenient random sample of 265 students from AIMST University was conducted by using pretested and validated questionnaires to gather information on the attitude, knowledge and perception of medical, pharmacy and dental students. RESULTS:  Of the 265 respondents in AIMST University, 100 of the respondents were male (37.7%) and 165 of them were female (62.3%). For the evaluation of knowledge and perception, males (Mean rank = 15.69±2.29) were having less adequate knowledge than females (Mean rank = 15.06±2.69). Among all races that participated in the study, Indians were having the most adequate knowledge than other races on Zika Virus (Mean rank = 14.93±2.22). Among the Faculty of Medicine, Pharmacy and Dentistry, Faculty of Medicine was having the most adequate knowledge than other faculties (Mean rank = 17.0±1.01). Year 4 (Mean rank = 15.06±2.69) students were having more adequate knowledge then Year 3 students (Mean rank = 15.25±2.29). CONCLUSIONS: Most of the students are having good knowledge