OBJECTIVES: Patient Reported Outcomes (PROs) play an important role in evaluating patient quality of life and comparative efficacy of various treatments. Another potential use of PROs is for chronic disease management, which can provide useful data to physicians and patients. We developed a novel web and phone based PROs tool for management of prostate cancer disease.  METHODS: PRO methods for prostate cancer were reviewed by analyzing published clinical studies. KOLs and patient advocacy groups were interviewed to obtain their input for design of PRO disease management tool. Recent technologies for developing such tools were reviewed by analyzing available electronic PRO tools. PROCDIM design was developed based on secondary research and primary interviews. RESULTS: PROCDIM was designed to capture patient reported outcomes data such as Quality of Life (using five attributes), adverse events (six commonly reported AEs), medications and OTC drugs history, PSA antigen score, past surgery and radiation therapy, and record of physician appointments. Patients could enter data into PROCDIM using web or phone (iphone or andriod) based systems. Data from PROCDIM could be emailed by the patient to the provider or could be downloaded by tethering a phone to a computer. Pilot data was captured by testing PROCDIM with physicians and patient advocacy groups. Based on interviews, PROCDIM was rated superior and highly user friendly compared to current chronic disease management tools. Patient outcomes data would be collected from a planned IRB approved study.  CONCLUSIONS: PROCDIM is a valuable tool to capture several patients reported outcomes and data for chronic disease management. Such tools could be used for collecting data for disease management, clinical trial, and observational studies for various chronic diseases.