OBJECTIVES: 1) To evaluate the relationship between asthma education and five measures of HRQoL - general health (GH), physical distress (PD), mental distress (MD), activity limitation (AL) and unhealthy days (UD), and 2) To find factors associated with  receiving asthma education. METHODS: Data of adult US asthmatic individuals were obtained from the 2009 BRFSS ACBS. Asthma education comprises of five components: receiving asthma management plan, monitor peak flow, recognize early signs or symptoms of an asthma episodes, respond to early signs or symptoms of an episode, and change environment to improve asthma. Those who received all five components were labeled as “asthma education” group and those who received none of the five components were labeled as “no asthma education” group. Group comparisons for HRQoL measures were done by Chi-square test using SAS 9.2® RESULTS: From a total of 1472 individuals identified in this study, 54.55 % did not receive all five components of asthma education. Individuals in the asthma education group reported significantly better GH (57.70 % vs. 49.81 %, p=0.002), fewer PD (64.28 % vs. 59.15 %, p=0.046) and fewer UD (52.32 % vs. 44.46 %, p=0.002). No significant differences were found for MD and AL due to high proportion of study individuals (>70%) reporting better HRQoL for these measures. Proportion of asthma education for all five components was significantly lower in; elderly, males, less than high school education, retired, and those with low income. CONCLUSIONS: Asthma education showed a positive impact on HRQoL measures – GH, PD and UD. Factors associated with non-receipt of all five asthma education components were age, gender, education, employment and income level. Interventions to encourage asthma education and overcome the inequality for the receipt of asthma education should be designed.