EFFECTS OF PATIENT-REPORTED HYPOGLYCAEMIA ON RESOURCE USE AND PATIENT WELL-BEING IN BELGIUM

Author(s)

Mathieu C1;D'Hooge D2, Vandebrouck T*2 1UZ Leuven campus Gasthuisberg, Leuven, Belgium, 2Novo Nordisk Pharma, Brussels, Belgium

OBJECTIVES: Limited data exist on the use of healthcare resources due to hypoglycaemia induced by insulin therapy in diabetes patients. This study investigated the frequency of patient-reported non‑severe hypoglycaemic events (NSHE) in type 1 (T1) and insulin-treated type 2 (T2) diabetes patients and their impact on healthcare resource use in Belgium. METHODS: T1 and T2 diabetes patients aged > 15 years were recruited via existing panels to complete four questionnaires collecting data at weekly intervals. In addition to demographics, data were collected on frequency of NSHE with a 7-day recall period, as well as data including impact on patient well-being, work productivity and healthcare resource use. NSHE was defined as an event with symptoms of hypoglycaemia, with or without blood glucose measurement (BGM), or low BGM without symptoms, which the patient could manage without assistance. Severe hypoglycaemic events (SHE), an event needing help from a third party to manage, were also reported. RESULTS: Overall, 412 patients (44% T1, 56% T2) completed 1148 patient-weeks. Mean NSHE per patient-week were 2.3 in T1 patients and 0.7 in T2 patients. Following their last NSHE, 64% patients reported feeling tired/fatigued, 59% feeling less alert and 37% feeling ill/uncomfortable. Over the 7 days following a NSHE, BGM test-strip use increased by 3.4 (mean). Of the 38% employed, 5% reported lost work time due to the last NSHE. Following daytime NSHE, 6% of T1 patients and 17% of T2 patients contacted a healthcare professional, plus 8% of T1 and 6% of T2 following a nocturnal NSHE. Mean annual frequency of SHE was 0.6. Of the 124 patients reporting a SHE, 17% required emergency visits. CONCLUSIONS: NSHE have an economic burden with a negative impact on patient well-being. However, the real burden of hypoglycaemia may be underestimated since few patients report events to a healthcare professional.

Conference/Value in Health Info

2013-05, ISPOR 2013, New Orleans, LA, USA

Value in Health, Vol. 16, No. 3 (May 2013)

Code

PDB58

Topic

Economic Evaluation

Topic Subcategory

Cost/Cost of Illness/Resource Use Studies

Disease

Diabetes/Endocrine/Metabolic Disorders

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