WINTERTIME SURGERY INCREASES THE RISK OF OSTEONECROSIS AFTER INTERNAL FIXATION OF FEMORAL NECK FRACTURE
Author(s)
Sebestyén A1, Gajdácsi J2, Boncz I3, Molics B4, Péter I5, Laczó A6, Juhász K1
1National Health Insurance Fund Administration, Pécs, Hungary, 2National Health Insurance Fund Administration, Budapest, Hungary, 3University of Pecs, Pecs, Hungary, 4University of Pécs, Pécs, Hungary, 5Zsigmondy Vilmos SPA Hospital, Harkány, Hungary, 6National Healthcare Service Center, Pécs, Hungary
OBJECTIVES: The changes of vitamin D level influencing bone metabolism are seasonal, the effect of seasons on femoral neck fracture healing is unknown. The aim of our study was to determine the effects of seasonal periodicity on incidence of osteonecrosis following primary osteosynthesis of femoral neck fractures in Hungarian elderly population. METHODS: This nationwide retrospective observational cohort study based on dataset of National Health Insurance Fund Administration. Patients over 60 years undergoing internal fixation after primary femoral neck fracture (ICD10-S7200) and were discharged in 2000 were identified. Inpatient cases developing osteonecrosis were registered during the 8 years follow-up. The following factors were evaluated: sex, age, type of fracture, season of surgical intervention, day of surgery, surgical delay and comorbidities. The effect of seasons on survival time was investigated by Kaplan–Meier analysis and log-rank test. The crude incidence rate ratios of osteonecrosis were calculated for factors. The impact of risk factors on the hazard of osteonecrosis was estimated by Cox proportional hazard model. RESULTS: CONCLUSIONS: Wintertime osteosynthesis increases the risk of osteonecrosis. The findings raise the possibility of association between seasonal changes in vitamin D levels and impaired fracture healing of femoral neck fracture. The results may help establish an effective strategy for the prevention of serious complications.
Conference/Value in Health Info
2015-11, ISPOR Europe 2015, Milan, Italy
Value in Health, Vol. 18, No. 7 (November 2015)
Code
PMS23
Topic
Epidemiology & Public Health
Disease
Musculoskeletal Disorders