OBJECTIVES: The purpose of the study is to investigate how the QOL of parents whose child had received pediatric kidney tranplantation(KT)  would change by delivering questionnaires for four times a year. METHODS: The QOL of thirty-one parents with a mean age of 38.5 yrs old (30 mothers, 1 father) whose child received KT at Toho Ohmori Hospital in Tokyo from May 2012 to March 2015 was measured using WHOQOL, GHQ, and VAS for four times; before, one month, three months, one year after KT.  The mean age of receipient patients was 5.8 yrs old (18 boys, 13 girls).  Congenital anomalies of the kidney and urinary tract were most frequent primary diseases.  Among them twenty-two children received dialysis before KT, and nine received preemtive KT.   RESULTS: Based on the results of WHOQOL, the QOL of parents dropped with a statistical difference one month after KT, compared with before KT (p=0.042), but rose at three months (p=0.0073), and maintained until one year. The QOL of parents with child with frequent infections was statistically lower than those without any infectionat three months after KT  (p=0.448) and one year after KT (P=0.0406).  The QOL scores of nineteen donor parents had a statistically higher QOL before KT, but reversed at one month after KT particurally in physical domain of WHOQOL, but became higher again at three month after KT, compared with the rest of parents.   CONCLUSIONS: The QOL of the parents would change in the process recovery of child, and with infection or other medical problems occurred, QOL reflected it, but three months after KT, QOL rose as high as before KT.