OBJECTIVES: The prevalence of pneumonia, meningitis and septicemia cases recorded among 50+ Hungarian population has been growing. One of the main reasons of the year by year higher occurrences is the ever ageing population, where the incidence is higher generating significant incremental resource utilization. METHODS: The study determines whether the probability of morbidity over 50+ has changed (using general linear model - GLM) and the direct health care cost of the three mentioned diseases based on the National Health Insurance Fund database. Cases and direct healthcare cost of inpatient, outpatient care, diagnostics and medication were defined with an analysis of the Hungarian population. The study that covers the 2005-2013 timeframe in 5 year age-groups does not calculates indirect burden. RESULTS: The research shows that the age increases the probability of disease. Between the age groups 40-49 and 50-54 the probability of disease increased by 26% (from GLM model, which is significant) and growing in each age-group. The prevalence of analyzed diseases among 50+ Hungarian population has increased by 10% between 2005 and 2013 resulting an incremental 2.34 billion HUF extra direct health care cost expenditure. Approximately 77% of this extra amount was used by the 65+ population. Worthy to note that the disease specific mortality among 50+ Hungarian population is 1.8 times higher in 2013 compared to 2005 and reached 18,954 inhabitants. Because of the disease specific death and direct health care cost an approx. 9.3 billion HUF direct health care burden was reported in year 2013 among the 50+ population. CONCLUSIONS: The health care attendance of pneumonia, meningitis and septicemia diseases effects a huge burden on the health care system that grows year by year. By the help of a targeted pneumococcal vaccination program a part of the ever growing yearly burden could be avoided.