OBJECTIVES: To analyze the inpatients direct medical costs and reimbursement rate of breast cancer based on national claimed database for urban employees and compare on the cost of different types of treatment. METHODS: Mechanical sampling was used to collect data on inpatients costs of breast cancer in 3 cities (Beijing, Shanghai and Chengdu) in China in 2011. 314 patients were screened into this study from national claimed database of urban employees. Statistics analysis and descriptive analysis were used to find out direct medical costs and reimbursement rate of patients hospitalized with breast cancer in different treatment type