RESULTS OF THE EQ-5D-3L VALUATION PROJECT FOR IRELAND
Author(s)
Reddy B1, Walsh C2, Barry M1, Kind P3, Adams R1
1National Centre for Pharmacoeconomics, Dublin, Ireland, 2University of Limerick, Limerick, Ireland, 3HSE University, St Petersburg, Russia
OBJECTIVES: The EQ-5D-3L is generic health status measure used as a basis for gauging public preferences regarding the severity of overall health states. This was the first such study of Irish health state preferences, and explored a number of innovative modifications to the 3L protocol. METHODS: A new approach to measuring worse than dead (WTD) preferences was used, which reduced the utility linearly by 0.1 units at a time (equivalent to the same leap in better than dead states). Several alternative model specifications (e.g. log-normalised interval regression, random /fixed effects and latent variable models) were considered. We also measured TTO values for experienced health states and for 30 5L states. RESULTS: The results of the fitted models corresponded well to each other. Interval regression appears to have had an impact on results acording to the level of censoring. The Irish population was shown to place a lower emphasis on pain states than the UK or other European tariffs, implying a higher perceived quality of life in such circumstances. The changes to the protocol on how to measure WTD states resulted in less extreme values overall. CONCLUSIONS: This is the first valuation of health state preferences in Ireland and introduces important methodological modifications to the TTO experiment and modelling of health states. It is an important contribution to the evaluation of the QALY in Ireland and addresses some of the challenges associated with TTO valuation previously.
Conference/Value in Health Info
2015-11, ISPOR Europe 2015, Milan, Italy
Value in Health, Vol. 18, No. 7 (November 2015)
Code
PIH43
Topic
Patient-Centered Research
Topic Subcategory
Stated Preference & Patient Satisfaction
Disease
Multiple Diseases