OBJECTIVES: Assess clinical characteristics and patterns of care among patients with G1 Hepatitis C virus (HCV) in EU. METHODS: A multi-center retrospective chart-review study of HCV patients was conducted in the EU (France/Germany/Italy/Spain/UK) in 4Q2014 to collect de-identified data on diagnosis, clinical status, and treatment patterns. Physicians were screened for duration of practice (≥3yrs) and patient volume (≥15 HCV patients/mo) and recruited from a large panel to be geographically representative. Medical charts of the next 10 consecutive HCV patients were abstracted. G1 HCV patient data was analyzed. RESULTS: CONCLUSIONS: In this cohort of G1 HCV patients, treatment rates and disease burden varied among studied countries in EU; only a small proportion of patients had undetectable VL or was not treated owing to achieving sustained viral response. Further research is warranted to assess the observed treatment patterns, effectiveness of regimens, and patient management strategies to alleviate patient burden.