TREATMENT PATTERN VISUALIZATION OF MEDICARE PATIENTS DIAGNOSED WITH RHEUMATOID ARTHRITIS AND INITIATING TUMOR NECROSIS FACTOR THERAPY

Author(s)

Baser O1, Wang L2, Xie L3, Yuce H41STATinMED Research/The University of Michigan, Ann Arbor, MI, USA, 2STATinMED Research, Dallas, TX, USA, 3STATinMED Research, Ann Arbor, MI, USA, 4New York City College of Technology-CUNY / STATinMED Research, New York, NY, USA

OBJECTIVES: In recent years, methodologies used in outcomes research have advanced. In a field where different disciplines interact frequently, a tool to communicate information clearly and effectively through graphical means has become a necessity. Using data visualization techniques, we present treatment patterns of patients diagnosed with rheumatoid arthritis (RA). METHODS: Using the 100% national Medicare data with Part D information, patients who are over age 65 and have had 2 diagnoses for RA at least 60 days apart were selected for the study. We identified patients who initiated therapy with tumor necrosis factor (TNF) agents. For 2 years after the initiation of TNF, we examined treatment patterns such as switching to another TNF, switching to a non-TNF, and drug discontinuation. Using a processing language, we created a data visualization tool to illustrate changes in treatment patterns after first, second and the third switches. RESULTS: A total of 50,455 RA patients initiated therapy with a TNF. 4.37% of these patients switched to another TNF, 5.81% switched to a non-TNF, 61.52% discontinued therapy and 28.31% continued their initial therapy. Among patients who switched to another TNF, 37.36% remained on the switched therapy, 46.71% discontinued, 8.40% switched to another TNF, and 7.54% switched to a non-TNF. In 2 years after TNF initiation, 7.03% of patients who switched twice after the initial TNF switched a third time to another TNF, while 51.35% continued their second switched drug, 35.68% discontinued their second switched TNF, and 5.95% switched to a non-TNF.  CONCLUSIONS: Treatment patterns can be difficult to present, especially if they were analyzed for subsequent years and switches. Data visualization tools can assist researchers in the effective presentation of these complicated flows.

Conference/Value in Health Info

2012-06, ISPOR 2012, Washington, D.C., USA

Value in Health, Vol. 15, No. 4 (June 2012)

Code

PMS6

Topic

Clinical Outcomes

Topic Subcategory

Comparative Effectiveness or Efficacy

Disease

Musculoskeletal Disorders

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