DATA VISUALIZATION OF TREATMENT PATTERNS OF MEDICARE PSORIATIC ARTHRITIS PATIENTS WHO INITIATE TUMOR NECROSIS FACTOR THERAPY

Author(s)

Baser O1, Wang L2, Xie L3, Yuce H41STATinMED Research/The University of Michigan, Ann Arbor, MI, USA, 2STATinMED Research, Dallas, TX, USA, 3STATinMED Research, Ann Arbor, MI, USA, 4New York City College of Technology-CUNY / STATinMED Research, New York, NY, USA

OBJECTIVES: Outcomes research methodologies need to advance and allow access by various disciplines as clinicians, epidemiologists, economists, and statisticians interact frequently. A data visualization tool can help present complex patterns more effectively to a diverse audience. METHODS: Patients over 65, with at least one diagnosis for PsA were selected for this study, using the 100% national Medicare data with Part D information.  We identified patients who initiated therapy with tumor necrosis factor (TNF) and non-TNF treatments. For 2 years after biologic initiation, the following treatment patterns were examined: switching to another TNF, switching to a non-TNF, and discontinuation. We created a data visualization tool using a processing language to show how patient treatment patterns change after the first and second drug switches. RESULTS: A total of 2921 patients initiated PsA therapy with a TNF agent. 6.44% of these patients switched to another TNF, 2.43% switched to a non-TNF, 51.11% discontinued therapy and 40.02% continued their initial therapy. Among patients who switched to another TNF, 50.53% remained on the switched therapy, 30.85% discontinued therapy, 18.09% switched to another TNF, and 0.53% switched to a non-TNF. In 2 years after TNF initiation, 11.76% of patients made a second switch from their initial TNF to a third TNF while 64.71% continued their second switched drug, 23.53% discontinued the second switched TNF and no patients switched to a non-TNF.  CONCLUSIONS: It can be difficult to present treatment patterns, especially when analyzing subsequent years and switches. Data visualization tools can help present these complicated flows effectively to a diverse health outcomes research audience.

Conference/Value in Health Info

2012-06, ISPOR 2012, Washington, D.C., USA

Value in Health, Vol. 15, No. 4 (June 2012)

Code

PMS5

Topic

Clinical Outcomes

Topic Subcategory

Comparative Effectiveness or Efficacy

Disease

Musculoskeletal Disorders

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