OBJECTIVES The objective of this study was to estimate the burden associated with primary hyperhidrosis by assessing patient’s health utilities, willingness to pay (WTP) for a complete cure and daily time spent in managing the condition. METHODS The data used in this study were collected under a longitudinal multi-stage research undertaken to develop and validate a new HRQoL instrument from patients with hyperhidrosis recruited through online social networking communities (Hyperhidrosis support group UK and International hyperhidrosis society) from January to August 2013. Only the baseline assessment is used in this analysis.  Disease severity was measured using the Hyperhidrosis Disease Severity Scale (2 = for tolerable sweating, 3 =…barely     tolerable sweating, 4 = intolerable sweating). The EuroQoL 5D-5L was used for assessing health utility index. RESULTS EQ-5D health utility index was lower in patients with more severe hyperhidrosis [mean utility value = .85± 0.13 for HDSS = 2, 0.8±.15 for HDSS = 3, and 0.69±.2 for HDSS = 4, chi-square = 25.86, df = 2, p < 0.001]. Further, the health utility index was .64 ± .22 for WTP £0, 0.81±0.16 for £ 1 to 49, .81±15 for  £ 50 to 99, .76±.16 for £100 to 199, .79± for £ 200 to 299, .71±.19 for £300 or more. Patients spent a mean of 50±134 minutes (HDSS = 2), 65±119 minutes (HDSS = 3) and 161±293 minutes (HDSS = 4) for daily management of hyperhidrosis. WTP showed the lowest correlation to disease severity. CONCLUSIONS The current study underscores the multidimensionality of the burden of hyperhidrosis, with all aspects showing greater impairment with greater disease severity. Health utility and daily time spent in managing the condition offered significant discrimination of patients.