OBJECTIVES: To assess the characteristics of SLE patients currently on Remission (Group-1), currently with active disease but not experiencing a flare (Group-2) and those who are experiencing flares (Group-3) in Europe (EU). METHODS: A multi-center medical chart review of adult (16-89 yrs) SLE patients was conducted in 1Q2014 among rheumatologists/internal medicine physicians in UK/France/Germany/Italy/Spain (5EU). Physicians were recruited from a geographically representative sample in each country. Approx. 5 consecutive eligible persistent active or relapse remitting SLE patients currently managed as part of usual care were identified. Physicians abstracted de-identified patient data on disease characteristics, lab values and treatment patterns. Patient disease status and humanistic burden was assessed by physician per clinical judgment & patient interaction. RESULTS: CONCLUSIONS: Over half of the SLE patients had an active disease while one-in-five were experiencing a flare in this study cohort, with significant variations observed within 5EU. Clinical and humanistic burden varied based on patient disease status, with highest burden observed among those experiencing flares.