OBJECTIVES: Socio-economic phenomena, caused by disease of children are reflected primarily in the formation of non-medical costs. Methodology for calculation of non-medical costs includes a number of parameters, including the cost of lost output by persons caring for children during the treatment period.  METHODS: The study involved patients from  Oncohematological Chelyabinsk Center for Children and Adolescents behalf of prof. V. Gerein    been treated in the period from 2008 to 2013. Patient selection was random. The basic condition for inclusion in the study was the availability of data necessary to meet the costs. The number of patients at this stage of the study was already 42 people. Age at diagnosis was 9 months to 12 years, the median age of the patients was 6,4 ± 5,6 years. All of the patients were in the hospital with their parents of working age. In the calculations have been included: - GRP Chelyabinsk region (Gross Regional Product-14 USD per day per capita )   and  GDP (Gross Domestic Product-44,4 USD per day per capita ), which amounted on average in 2008-2012. The formula for the calculation of total costs:E $ = Nd x GRP / GDP (Nd-the number of days of disability)  RESULTS: Comparing the various cost components of treatment revealed that the indirect costs are 66% of the total amount of all expenses for medical treatment.  State losses caused by non-working period of hospitalized for care people and non-produced Gross Regional Product are 7758,5 ± 1076,1 USD per capita. Losses of GDP are 21449,6 ± 3748,8 USD per capita.  CONCLUSIONS:  The formation of  regional budgets should be done with consideration of  big loss connected with disability of people hospitalized for the  care of the  a sick child, adjusted for and with GRP/GDP taken into account of  big potion non-medical costs .