OBJECTIVES: The object of analysis is the presentation of results from the Heart-Vessel Diseases Prophylactic Program for 40 and 50 year old residents of Wroclaw conducted from 1998 to 2008. 43 thousand people took part in the program. The aim of the program was to counteract health, life and disability risks which are among of the main causes of death in Poland – heart-vessel diseases as well as primary and secondary prevention and analysis of the appearance of the risk factors of these diseases. METHODS: Outcomes analysis was used to evaluate the program. The analysis was carried out on the health results of two groups of participants of the program. The first group comprised of 50 year old people invited to the program for the first time. The second group comprised of the 50 year old participants who had already taken part in the program 10 years earlier. The participants of the program underwent health education concerning prophylactics of heart-vessel diseases and they were presented with coefficients such as BMI, triglyceride levels, cholesterol, glucose and blood pressure. A health profile was made for every participant. RESULTS: The health situation changed in almost 1/3 of the people in the group that took part in the program 10 years ago. The modifiable risk factors of heart vessel diseases underwent changes: an increase in protein intake (36%), increased physical activity (27%) as well as carrying out systematic blood sugar controls (22%).11% of the participants of the program, who were analyzed for the second time, thought that the health education carried out then, affected their life styles to a greater extent. CONCLUSIONS:   After evaluation period of 10 years, efficiency of program and activities were analyzed and shown. Outcome analysis verified that 10 years of prophylactic program, reduced exposure to risk factor of DOTCS. We also selected an areas for future modification and improvement. Due to outcomes analysis, regional politics of health protection was adequate to epidemiological factors and social needs of regions.