OBJECTIVES: This study examined the asthma medications prescribing patterns among pediatric asthma visits in ambulatory care settings in the United States. METHODS: A retrospective cross-sectional analysis of National Ambulatory Medical Care Survey (NAMCS) and the outpatient data of the National Hospital Ambulatory Medical Care Survey (NHAMCS) of year 2006-2007 was conducted involving children aged less than 18 years and diagnosed with asthma (ICD-9-CM 493.XX). The analyses focused on medications based on the guidelines of the National Asthma Education and Prevention Program (NAEPP). Descriptive statistics was used to examine the prescribing pattern. RESULTS: According to NAMCS and NHAMCS, there were18 million (0.87%) physician office visits by children with asthma. Long Acting β2 Agonist was highly prescribed among (57.50%) office visits, followed by Leukotrine Modifiers (29.91%) and Inhaled Corticosteroids (27.88%). Oral Corticosteroids and Short Acting β2 Agonist were prescribed in 15.99%, and 14.18% of office visits, respectively. In terms of individual medicines, Albuterol, was mostly prescribed among 10.43 million visits, followed by Montelukast, 5.42 million visits. Prednisolone was prescribed in 2.71 million visits and Levalbuterol was prescribed in 2.36 million visits. CONCLUSIONS: Long Acting β2 Agonist and Leukotrine Modifiers was the most highly prescribed medication class and Albuterol and Montelukast were highly prescribed individual medications in pediatrics asthma ambulatory care visits in the United States.