OBJECTIVES: To determine the annual direct cost of treatment of vaginitis in Turkey. METHODS: A consensus panel approach was implemented in order to define the vaginitis management pattern and relevant resource utilization. The panel consisted of 11 gynecologists, affiliated with the existing patterns of outpatient health care settings. Cost analysis was based on the estimation of 1 year direct cost of treatment, based on 2008 fees and prices, expressed in dollars. RESULTS: Total cost of vaginitis treatment was found to be $81.6 per patient. This cost covered partner expenditures. The disbursement included outpatient clinic fees and pharmacotherapy. The laboratory tests were included in the outpatient clinic fees according to new Social Security Institution (SSI) regulations. CONCLUSIONS: Altough the prevalence and causes of vaginitis are uncertain, in part because the condition is so often self-diagnosed and self-treated, women often seek medical care for vaginal complaints. SSI may have to reimburse vaginitis treatment more than once for a woman in a year. Therefore, the SSI should know the cost of vaginitis treatment in order to make a budget plan among other treatments.