OBJECTIVES: Russian Society of Pharmacoeconomics and Outcomes Research jointly to Russian Hemophilia Society carried out postal and telephone health survey of all known Russian patients with hemophilia in the period 2009-2010. Aim of the study was to assess health status, treatment patterns and quality of life in patients with inhibitory form of hemophilia. METHODS: Postal and telephone health survey. The questionnaire contained questions on clotting factor level and presence of antibodies to it, names of used medications. Health-related quality of life was assessed with self-administrated validated version of Russian version of Euroqol-5D questionnaire, comprising a dimensions of health and visual-analog scale. Statistical analysis of data was performed with χ² criteria. RESULTS: The results of principal methods of treating inhibitory form of hemophilia in 60 patients with haemophilia A were analysed. Health-related quality of life was assessed for patients older than 11 years (n = 56). More than half of patients reported problems within each of EQ-5D dimensions of health. Thus 76.6% of patients reported of problems with mobility; 48.4% of patients informed of difficulties with self-care; 75% of patients had difficulties with usual activity; 81.7% of patients reported of presence of pain or discomfort; 50.1% of patients had an anxiety or depression. The average value of quality of life evaluated with visual-analog scale (VAS) was 0.57 (SD 0.17), median – 0.52. CONCLUSIONS: The study of quality of life in patients with hereditary coagulopathies was performed for the first time in Russian. Results of the study shown high rate of pain/discomfort, of problems with movement, usual activity and low rate of problem with self-care and anxiety/depression.