OBJECTIVES: To determine the cost of Dupuytren´s contracture in the Czech Republic. METHODS: Survey among general surgery specialists and orthopedic surgeons (panel of total 9 surgeons) conducted. The assessment itself was done using a classical Delphi panel method, combined with data from medical charts and/or hospital information systems. Besides the surgeons, also rehabilitation specialists (to cover costs for rehabilitation) and internal medicine specialists (to cover complications) were included into the panel. RESULTS: If indirect costs (productivity loss) are included, they represent the major part of all costs (76 %). In case of direct cost inclusion, rehabilitation stands for more than 50% of costs, followed by surgery costs (almost 30 %). Mean direct costs (1 operation field) are estimated at about 12,000 CZK with a variation of 9 200 to 14,400 CZK.  If indirect costs (productivity loss) are included, total costs increase dramatically, arriving at mean costs of almost 50 thousand CZK (21,800 to 90,200 CZK). CONCLUSIONS: Cost of Dupuytren´s contracture range from 21,800 to 90 200 CZK if indirect cost included. Indirect cost represent  76% of all costs.