OBJECTIVES: To analyze and predict trends in utilization of preventive care services in a United States population using a national database. Several national reports and evidence in literature indicate disparities in the utilization of preventive care services but only few have predicted utilization patterns of preventive care services. METHODS: The 2007 Medical Expenditure Panel Survey (MEPS), a national probability sample survey of the ambulatory civilian US population, was analyzed to determine demographic patterns of utilization. Utilization of blood pressure screening, cancer screening (mammography, colonoscopy/sigmoidoscopy, pap smear and breast), cholesterol and dental checkup and flu vaccination were used as the dependent variables while age, gender, race/ ethnicity, annual income insurance status and perceived health status were used as independent variables. Descriptive statistics were used to describe the population; univariate chi-squared analysis was used to determine group differences for the categorical variables. Multivariate logistic regression model was built to predict odds of utilization of services. All analyses were carried out using SAS v9.1. RESULTS: Utilization of preventive care services was found to be high for blood pressure (n=17,959, 89.0%) and cholesterol (n=14,956, 94.7%) checkup and low for flu vaccination (n=30,964, 21.2%). Significant chi square differences in utilization of preventive care services were found for most of the dependent variables (p<0.001), save for colonoscopy/sigmoidoscopy screening. Regression model showed that young women (20-30 years) with higher income were more likely to obtain breast exams (OR=10.584; CI=4.312-25.980) compared with young women earning lower income (